SCHEMBL2328028

SCHEMBL2328028

CCOC(=O)[C@H](CSC)NC(=O)c1ccccc1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 3/20 0.49
FNTB P49356 3/20 0.49
CLPP Q16740 2/20 0.47
LMNA P02545 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CHRNB2 P17787 2/20 0.45
CHRNB4 P30926 2/20 0.45
CHRNA3 P32297 2/20 0.45
CHRNA4 P43681 2/20 0.45
PGGT1B P53609 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
SCN1A P35498 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ELANE P08246 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27974661 1.00 FNTA (0.49) FNTAFNTBCLPPLMNAMEN1
SCHEMBL2333712 0.90 FNTA (0.59) FNTAFNTBCLPPMEN1KMT2A
SCHEMBL28813122 0.90 FNTA (0.59) FNTAFNTBCLPPMEN1KMT2A
SCHEMBL2328139 0.89 FNTA (0.53) FNTAFNTBCLPPKMT2APGGT1B
SCHEMBL2328137 0.89 FNTA (0.53) FNTAFNTBCLPPKMT2APGGT1B
SCHEMBL2330832 0.82 CLPP (0.46) CLPPLMNAMEN1KMT2ACHRNB2
SCHEMBL2323583 0.82 KMT2A (0.52) LMNAKMT2AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL2323581 0.82 KMT2A (0.52) LMNAKMT2AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL2326177 0.81 CLPP (0.47) CLPPLMNAMEN1KMT2ACHRNB2
SCHEMBL2327912 0.80 FNTA (0.52) FNTAFNTBCLPPKMT2APGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356979-B1 ANTI-WRINKLE AGENTS POLA CHEM IND INC (JP) 2017-10-25 EP disclosed
EP-3173063-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2017-05-31 EP disclosed
US-8835498-B2 Anti-wrinkle agents POLA CHEMICAL INDUSTRIES INC. (JP) 2014-09-16 US disclosed
US-20110245343-A1 ANTI-WRINKLE AGENTS POLA CHEMICAL INDUSTRIES INC. (JP) 2011-10-06 US disclosed
EP-2356979-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2011-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245343-A1 ANTI-WRINKLE AGENTS GLA, H1-4, H1-3 FNTA 4644/4885FNTB 4431/4885CLPP 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.