Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618112 | 0.83 | POLB (0.34) | ALDH1A1LMNAPOLB | |
| SCHEMBL28404488 | 0.83 | POLB (0.34) | ALDH1A1LMNAPOLB | |
| SCHEMBL20459499 | 0.78 | ALDH1A1 (0.32) | ALDH1A1LMNAPOLB | |
| SCHEMBL18380858 | 0.74 | — | — | |
| SCHEMBL10704868 | 0.71 | — | — | |
| SCHEMBL14161071 | 0.69 | — | — | |
| SCHEMBL13911498 | 0.67 | ALDH1A1 (0.32) | ALDH1A1LMNAPOLB | |
| SCHEMBL12582193 | 0.66 | — | — | |
| SCHEMBL12462736 | 0.66 | — | — | |
| SCHEMBL21950877 | 0.64 | POLB (0.35) | ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189041-B1 | TETRAHYDROISOQUINOLINE DERIVED PRMT5-INHIBITORS | CTXT PTY LTD (AU) | 2021-04-28 | — | — | EP | disclosed |