Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38661308 | 0.85 | S1PR1 (0.43) | EGFRACACBS1PR1 | |
| SCHEMBL557714 | 0.82 | S1PR1 (0.50) | ACACBS1PR1 | |
| SCHEMBL5410860 | 0.81 | S1PR1 (0.39) | ACACBS1PR1 | |
| SCHEMBL5415896 | 0.81 | S1PR1 (0.39) | ACACBS1PR1 | |
| SCHEMBL5410863 | 0.81 | S1PR1 (0.39) | ACACBS1PR1 | |
| SCHEMBL289843 | 0.81 | EGFR (0.41) | EGFRS1PR1 | |
| SCHEMBL17559337 | 0.80 | GPR119 (0.49) | EGFRS1PR1 | |
| SCHEMBL5399844 | 0.80 | S1PR1 (0.52) | ACACBS1PR1 | |
| SCHEMBL5405665 | 0.80 | S1PR1 (0.52) | ACACBS1PR1 | |
| SCHEMBL19473361 | 0.79 | S1PR1 (0.34) | EGFRACACBS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189041-B1 | TETRAHYDROISOQUINOLINE DERIVED PRMT5-INHIBITORS | CTXT PTY LTD (AU) | 2021-04-28 | — | — | EP | disclosed |