SCHEMBL23281186

SCHEMBL23281186

c1ccc(-c2ccc(Nc3ccc4oc5c6ccccc6ccc5c4c3)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 10/20 0.45
CYP1B1 Q16678 9/20 0.45
CYP1A2 P05177 9/20 0.45
MAPT P10636 6/20 0.45
ALDH1A1 P00352 5/20 0.45
HPGD P15428 4/20 0.45
HSD17B10 Q99714 4/20 0.45
KDM4E B2RXH2 4/20 0.45
TSHR P16473 3/20 0.45
ABCG2 Q9UNQ0 3/20 0.45
CYP3A4 P08684 2/20 0.45
TP53 P04637 2/20 0.45
PRKDC P78527 2/20 0.45
PDE5A O76074 1/20 0.45
ABCB1 P08183 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP19A1 P11511 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2B6 P20813 1/20 0.45
TACR2 P21452 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18803790 0.95 CYP1A1 (0.45) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL18471178 0.93 ALDH1A1 (0.49) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL17283767 0.90 CYP1A1 (0.46) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL23168502 0.87 ALDH1A1 (0.49) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL27050226 0.86 CYP1A1 (0.51) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL25622501 0.84 MAPT (0.42) MAPTALDH1A1HPGDHSD17B10KDM4E
SCHEMBL24827039 0.84 ALDH1A1 (0.44) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL17382502 0.84 ALDH1A1 (0.40) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL23423605 0.83 ABCG2 (0.47) CYP1A1CYP1A2MAPTALDH1A1HPGD
SCHEMBL17283519 0.83 CYP1A1 (0.36) CYP1A1CYP1B1CYP1A2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021080334-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-04-29 WO disclosed