SCHEMBL232815

SCHEMBL232815

FC(F)(F)C1CCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL325293 1.00
SCHEMBL894123 1.00
Ammonia Solution, Strong SCHEMBL29073423 0.97 KDM4E (0.38)
Hydrochloric Acid SCHEMBL17202017 0.97 KDM4E (0.42)
Hydrochloric Acid SCHEMBL17202018 0.97 KDM4E (0.42)
Hydrochloric Acid SCHEMBL21817810 0.97 KDM4E (0.42)
SCHEMBL2246580 0.92 CYP2D6 (0.34)
SCHEMBL12100332 0.92 CYP2D6 (0.34)
SCHEMBL1036841 0.92 CYP2D6 (0.34)
SCHEMBL1110677 0.90 CYP2D6 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 584 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070254881-A1 Pyrazole Derivative DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-11-01 US claimed
EP-1785418-A1 PYRAZOLE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2007-05-16 EP claimed
US-5254696-A Intermediates for herbicides, nematocides BAYER AKTIENGESELLSCHAFT (DE) 1993-10-19 US claimed
EP-0475236-A1 N-acylpyrrolidine derivatives BAYER AG (DE) 1992-03-18 EP claimed
EP-3802500-B1 MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF CRINETICS PHARMACEUTICALS INC (US) 2026-05-27 EP disclosed
EP-4737470-A2 C10-ALKYLENE SUBSTITUTED 13-MEMBERED MACROLIDES AND USES THEREOF Zikani Therapeutics, Inc. (US) 2026-05-06 EP disclosed
US-20260103455-A1 ULK3 INHIBITORS AND USES THEREOF H LEE MOFFITT CANCER CT & RES (US) 2026-04-16 US disclosed
EP-4724431-A1 BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND USE THEREOF Beone Medicines I GmbH (CH) 2026-04-15 EP disclosed
US-20260085053-A1 BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND THE USE THEREOF BEONE MEDICINES I GMBH (CH) 2026-03-26 US disclosed
US-12577257-B2 Heterocyclic compounds HOFFMANN-LA ROCHE INC. (US) 2026-03-17 US disclosed
US-20260069571-A1 DDR1 AND DDR2 INHIBITORS FOR THE TREATEMENT OF CANCER AND FIBROTIC DISEASES REDX PHARMA PLC (GB) 2026-03-12 US disclosed
US-12558341-B2 Oral complement factor D inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2026-02-24 US disclosed
WO-2004056815-A1 PYRAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-07-08 WO disclosed
EP-1433788-A1 Pyrazole-derivatives as factor Xa inhibitors Aventis Pharma Deutschland GmbH (DE) 2004-06-30 EP disclosed
US-5256795-A Herbicides, nemat cides BAYER AKTIENGESELLSCHAFT (DE) 1993-10-26 US disclosed
US-5254696-A Intermediates for herbicides, nematocides BAYER AKTIENGESELLSCHAFT (DE) 1993-10-19 US disclosed
US-5204471-A α-trifluoromethyl-substituted, saturated bicyclic amines BAYER AKTIENGESELLSCHAFT (DE) 1993-04-20 US disclosed
EP-0527385-A1 Alpha-trifluoromethyl substituted, saturated bicyclic amines and process for their preparation BAYER AG (DE) 1993-02-17 EP disclosed
US-5171355-A Herbicides, nematocides BAYER AKTIENGESELLSCHAFT (DE) 1992-12-15 US disclosed
EP-0475236-A1 N-acylpyrrolidine derivatives BAYER AG (DE) 1992-03-18 EP disclosed