Sugi Predict

Sugi Predict / Compounds / SCHEMBL1036841

SCHEMBL1036841

SCHEMBL1036841

FC(F)(F)C1CCCCN1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 0.34
▸ CYP1A2 P05177 2/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ RAB9A P51151 1/20 0.34
▸ FDPS P14324 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ TSHR P16473 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ MLNR O43193 1/20 0.30
▸ ABCB11 O95342 1/20 0.30
▸ EGFR P00533 1/20 0.30
▸ FYN P06241 1/20 0.30
▸ CHRM2 P08172 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12100332 1.00 CYP2D6 (0.34) CYP2D6CYP1A2KDM4ENPC1HPGD
SCHEMBL2246580 1.00 CYP2D6 (0.34) CYP2D6CYP1A2KDM4ENPC1HPGD
SCHEMBL1110628 0.97 CYP2D6 (0.33) CYP2D6CYP1A2KDM4ENPC1HPGD
SCHEMBL1110703 0.97 CYP2D6 (0.33) CYP2D6CYP1A2KDM4ENPC1HPGD
SCHEMBL1110677 0.97 CYP2D6 (0.33) CYP2D6CYP1A2KDM4ENPC1HPGD
Hydrochloric Acid SCHEMBL1032821 0.97 KDM4E (0.37) CYP2D6CYP1A2KDM4ENPC1HPGD
SCHEMBL325293 0.92 — —
SCHEMBL894123 0.92 — —
SCHEMBL232815 0.92 — —
Hydrochloric Acid SCHEMBL17202018 0.90 KDM4E (0.42) CYP2D6CYP1A2KDM4ENPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903522-A Synthesis method of 1-carbobenzoxy-6-trifluoromethyl piperidine-3-methyl formate 南通敏言生物医药科技有限公司 2023-10-20 — — CN claimed
US-20090118286-A1 Heterobicyclic Acrylamides BAYER CROPSCIENCE AG (DE) 2009-05-07 — — US claimed
CN-101171255-A Heterobicyclic acrylamides BAYER CROPSCIENCE AG (DE) 2008-04-30 — — CN claimed
US-20260001877-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED (US) 2026-01-01 — — US disclosed
US-20260001887-A1 CYCLIN-DEPENDENT KINASE INHIBITORS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2026-01-01 — — US disclosed
US-12491503-B2 Hydrogenation process of oxime derivatives SYNGENTA CROP PROTECTION AG (CH) 2025-12-09 — — US disclosed
US-20250333406-A1 SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF LYSOWAY THERAPEUTICS INC (US) 2025-10-30 — — US disclosed
EP-4618755-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2025-09-24 — — EP disclosed
US-20250270188-A1 NLRP3 INFLAMMASOME INHIBITORS NOVARTIS AG (CH) 2025-08-28 — — US disclosed
US-20250129044-A1 PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS XENON PHARMACEUTICALS INC. (CA) 2025-04-24 — — US disclosed
EP-4541422-A2 QUINOLINE DERIVATIVES AS ALPHA4BETA7 INTEGRIN INHIBITORS Gilead Sciences, Inc. (US) 2025-04-23 — — EP disclosed
US-20070004722-A1 1,2,4-Thiadazole compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-04 — — US disclosed
WO-2006094666-A1 HETEROBICYCLIC ACRYLAMIDES BAYER CROPSCIENCE AG (DE) 2006-09-14 — — WO disclosed
WO-2003062265-A2 NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS SCHERING CORPORATION (US) 2003-07-31 — — WO disclosed
US-5605926-A PROPHYLAXIS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-25 — — US disclosed
US-5430151-A Treatment of aids, pneumonia, caprine arthritis encephalitis, leukemia and immmunodeficiency BAYER AKTIENGESELLSCHAFT (DE) 1995-07-04 — — US disclosed
CN-1087083-A The intermediates preparation of synthetic 3-amino piperidine derivatives PFIZER (US) 1994-05-25 — — CN disclosed
US-5204471-A α-trifluoromethyl-substituted, saturated bicyclic amines BAYER AKTIENGESELLSCHAFT (DE) 1993-04-20 — — US disclosed
EP-0528242-A2 Trifluoromethyl containing pseudopeptides BAYER AG (DE) 1993-02-24 — — EP disclosed
CN-1053060-A 3-aminopiperidine derivatives and related nitrogen-containing heterocycles PFIZER (US) 1991-07-17 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129044-A1 PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS SCN1B, SCN1A, SCN2B CYP2D6 398/4885CYP1A2 284/4885KDM4E 1340/4885
US-12491503-B2 Hydrogenation process of oxime derivatives HMOX2, HAO2, PRDX5 CYP2D6 298/4885CYP1A2 185/4885KDM4E 1418/4885
US-20260001877-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN CNR1, SCN1B, OPRL1 CYP2D6 422/4885CYP1A2 1296/4885KDM4E 4437/4885
US-20090118286-A1 Heterobicyclic Acrylamides CCNB1, C3AR1, CCNA2 CYP2D6 567/4885CYP1A2 86/4885KDM4E 4621/4885
US-20260001887-A1 CYCLIN-DEPENDENT KINASE INHIBITORS CDK4, CCNC, CDK2 CYP2D6 2403/4885CYP1A2 3017/4885KDM4E 1289/4885
US-20070004722-A1 1,2,4-Thiadazole compounds and use thereof CYP4F3, CYP4B1, CYP4X1 CYP2D6 969/4885CYP1A2 39/4885KDM4E 950/4885
US-20250333406-A1 SULFONYL CYCLIC DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF STOML2, ATP2A3, ATP2A1 CYP2D6 3260/4885CYP1A2 4676/4885KDM4E 3136/4885
US-20250270188-A1 NLRP3 INFLAMMASOME INHIBITORS NLRP3, NLRP1, NOD1 CYP2D6 2270/4885CYP1A2 839/4885KDM4E 2289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.