SCHEMBL2328274

SCHEMBL2328274

CC(C)OP(=O)(CCCCC(P(=O)(OC(C)C)OC(C)C)P(=O)(OC(C)C)OC(C)C)OC(C)C

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 9/20 0.38
CTSA P10619 1/20 0.34
ACHE P22303 1/20 0.34
FDPS P14324 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2322178 0.94 HMGCR (0.39) HMGCRCTSAACHE
SCHEMBL9537924 0.87 HMGCR (0.42) HMGCRCTSAACHEFDPS
SCHEMBL11514172 0.87 CTSA (0.43) CTSAACHE
SCHEMBL11516051 0.84 CTSA (0.42) CTSAACHE
SCHEMBL4736507 0.84 CTSA (0.42) CTSAACHE
SCHEMBL11514169 0.84 CTSA (0.42) CTSAACHE
SCHEMBL11515008 0.82 CTSA (0.43) HMGCRCTSAACHE
SCHEMBL525985 0.82 CTSA (0.48) HMGCRCTSAACHE
SCHEMBL5328861 0.79 HMGCR (0.38) HMGCRCTSAACHEFDPS
SCHEMBL4736504 0.79 FDPS (0.55) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1351722-B2 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2016-02-17 EP claimed
US-20140316533-A1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2014-10-23 US claimed
US-RE43793-E1 Endosseous implant UNIVERSITE DE GENEVE (CH) 2012-11-06 US claimed
US-20120258148-A1 ENDOSSEOUS IMPLANT DESCOUTS PIERRE (FR) 2012-10-11 US claimed
US-20100234900-A1 ENDOSSEOUS IMPLANT DESCOUTS PIERRE 2010-09-16 US claimed
US-7727540-B2 surface of implant is made from titanium or titanium alloy, implant having smooth or rough surface texture, wherein surface has been treated with organic phosphonate compound or pharmaceutically acceptable salt or ester or amide thereof; for human or animal bone UNIVERSITE DE GENEVE (CH) 2010-06-01 US claimed
US-7090496-B2 Endosseous implant UNIVERSITE DE GENEVE (CH) 2006-08-15 US claimed
EP-1343545-B1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2006-07-05 EP claimed
EP-1351722-B1 ENDOSSEOUS IMPLANT UNIV GENEVE (CH) 2006-07-05 EP claimed
US-20040054422-A1 Endosseous implant UNIVERSITE DE GENEVE (CH) 2004-03-18 US claimed
US-20040049287-A1 Surface treated with a phosphonic acid, ester, amide or salt; orthopaedic prostheses; bone replacements or reinforcements, dentistry UNIVERSITE DE GENEVE (CH) 2004-03-11 US claimed
EP-1351722-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2003-10-15 EP claimed
EP-1343545-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2003-09-17 EP claimed
WO-2002040075-A1 ENDOSSEOUS IMPLANT UNIVERSITÉ DE GENÈVE (CH) 2002-05-23 WO claimed
WO-2002040074-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2002-05-23 WO claimed
EP-1698357-B1 POLYPHOSPHONIC ACIDS AND DERIVATIVES THEREOF UNIV GENEVE (CH) 2019-06-26 EP disclosed
US-9730795-B2 Endosseous implant UNIVERSITE DE GENEVE (CH) 2017-08-15 US disclosed
EP-1343545-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2003-09-17 EP disclosed
WO-2002040075-A1 ENDOSSEOUS IMPLANT UNIVERSITÉ DE GENÈVE (CH) 2002-05-23 WO disclosed
WO-2002040074-A1 ENDOSSEOUS IMPLANT UNIVERSITE DE GENEVE (CH) 2002-05-23 WO disclosed