Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CDC25A | P30304 | 2/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23282983 | 1.00 | VDR (0.59) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL23282986 | 0.90 | VDR (0.57) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL23282982 | 0.90 | VDR (0.57) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL4735308 | 0.89 | VDR (0.58) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL11530918 | 0.88 | VDR (0.77) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL11530914 | 0.88 | VDR (0.77) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL4740075 | 0.86 | VDR (0.56) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL13017807 | 0.86 | VDR (0.56) | VDRUSP2CDC25AABCC4POLA1 | |
| SCHEMBL23805655 | 0.86 | GPBAR1 (0.71) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL20367558 | 0.86 | GPBAR1 (0.71) | VDRUSP2GPBAR1CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812392-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | Sage Therapeutics, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |