Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | DRD3 | P35462 | 6/20 | 0.50 |
| ▸ | DRD4 | P21917 | 4/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24146933 | 0.80 | — | — | |
| SCHEMBL24035779 | 0.77 | DRD2 (0.50) | DRD2DRD3DRD4 | |
| SCHEMBL18338393 | 0.77 | DRD2 (0.54) | DRD2DRD3DRD4 | |
| SCHEMBL26176843 | 0.77 | DRD2 (0.50) | DRD2DRD3DRD4 | |
| SCHEMBL21243318 | 0.75 | DRD2 (0.46) | DRD2DRD3DRD4 | |
| SCHEMBL25086430 | 0.73 | DRD2 (0.50) | DRD2DRD3DRD4 | |
| SCHEMBL22200752 | 0.73 | DRD2 (0.54) | DRD2DRD3DRD4 | |
| SCHEMBL22200763 | 0.73 | DRD2 (0.57) | DRD2DRD3DRD4 | |
| SCHEMBL21672105 | 0.73 | DRD2 (0.50) | DRD2DRD3DRD4 | |
| SCHEMBL26114431 | 0.69 | DRD2 (0.33) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021080015-A1 | MODULATORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-04-29 | — | — | WO | disclosed |