Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.70 |
| ▸ | F2 | P00734 | 4/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325190 | 0.92 | F10 (0.68) | F10F2 | |
| SCHEMBL2329777 | 0.91 | F10 (0.71) | F10F2 | |
| SCHEMBL2328893 | 0.88 | F10 (0.71) | F10F2 | |
| SCHEMBL2329162 | 0.87 | F10 (0.57) | F10F2 | |
| SCHEMBL2335132 | 0.87 | F10 (0.53) | F10F2ROCK2ROCK1 | |
| SCHEMBL2329112 | 0.87 | F10 (0.62) | F10F2 | |
| SCHEMBL2329140 | 0.86 | F10 (0.73) | F10F2 | |
| SCHEMBL2328169 | 0.84 | F10 (0.70) | F10F2 | |
| SCHEMBL2329170 | 0.84 | F10 (0.72) | F10F2 | |
| SCHEMBL2330450 | 0.83 | F10 (0.69) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-B1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2011-08-17 | — | — | EP | disclosed |
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |