SCHEMBL2329162

SCHEMBL2329162

Cc1ccc(S(=O)(=O)N[C@H]2CCN(Cc3cccc(C#N)c3)C2=O)cc1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.57
F2 P00734 9/20 0.57
PLG P00747 1/20 0.51
PROC P04070 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328893 0.91 F10 (0.71) F10F2PLGPROC
SCHEMBL2328991 0.91 F10 (0.71) F10F2PLGPROC
SCHEMBL2325190 0.89 F10 (0.68) F10F2PLGPROC
SCHEMBL2328169 0.87 F10 (0.70) F10F2PLGPROC
SCHEMBL2328567 0.87 F10 (0.70) F10F2
SCHEMBL2330450 0.87 F10 (0.69) F10F2PLGPROC
SCHEMBL2329140 0.85 F10 (0.73) F10F2
SCHEMBL2330519 0.85 F10 (0.51) F10F2PLGPROC
SCHEMBL2329170 0.85 F10 (0.72) F10F2PLGPROC
SCHEMBL2329385 0.85 F10 (0.71) F10F2PLGPROC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853618-B1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMA INC (US) 2011-08-17 EP disclosed
US-5958918-A Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. 1999-09-28 US disclosed