SCHEMBL23285692

SCHEMBL23285692

C/C=C/C=C(\Cl)c1ccccc1OC(=O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.57
KMT2A Q03164 4/20 0.47
MAPT P10636 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 2/20 0.45
ELANE P08246 1/20 0.44
HSD17B10 Q99714 4/20 0.43
LMNA P02545 3/20 0.43
KDM4E B2RXH2 3/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
ESR1 P03372 3/20 0.42
ESR2 Q92731 2/20 0.42
MEN1 O00255 1/20 0.42
JAK2 O60674 1/20 0.42
USP2 O75604 1/20 0.42
ALOX15 P16050 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 3/20 0.42
PRSS1 P07477 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23276223 0.84 SLC6A3 (0.58) SLC6A3KMT2AMAPTSMN1; SMN2GAA
SCHEMBL23275580 0.84 SLC6A3 (0.58) SLC6A3KMT2AMAPTSMN1; SMN2GAA
SCHEMBL23285686 0.82 SLC6A3 (0.56) SLC6A3KMT2AMAPTSMN1; SMN2GAA
SCHEMBL26092280 0.82 SLC6A3 (0.56) SLC6A3KMT2AMAPTSMN1; SMN2GAA
SCHEMBL26094343 0.81 SLC6A3 (0.49) SLC6A3KMT2AMAPTSMN1; SMN2GAA
SCHEMBL26490212 0.81 SLC6A3 (0.49) SLC6A3KMT2AMAPTSMN1; SMN2GAA
SCHEMBL10780235 0.78 SLC6A3 (0.67) SLC6A3KMT2AMAPTSMN1; SMN2GAA
SCHEMBL26091761 0.78 SLC6A3 (0.51) SLC6A3KMT2AMAPTSMN1; SMN2GAA
SCHEMBL26490205 0.78 SLC6A3 (0.51) SLC6A3KMT2AMAPTSMN1; SMN2GAA
SCHEMBL11309362 0.76 SLC6A3 (0.69) SLC6A3KMT2AMAPTSMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021077194-A1 PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A (BR) 2021-04-29 WO disclosed