⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42512 | 0.83 | — | — | |
| SCHEMBL294158 | 0.81 | — | — | |
| SCHEMBL7305201 | 0.79 | EPHX1 (0.67) | — | |
| SCHEMBL4811184 | 0.79 | EPHX1 (0.67) | — | |
| SCHEMBL7300285 | 0.79 | EPHX1 (0.67) | — | |
| SCHEMBL8930393 | 0.79 | EPHX1 (0.67) | — | |
| SCHEMBL10702251 | 0.79 | EPHX1 (0.67) | — | |
| SCHEMBL7472317 | 0.79 | EPHX1 (0.67) | — | |
| SCHEMBL3842001 | 0.79 | EPHX1 (0.67) | — | |
| SCHEMBL8355975 | 0.79 | EPHX1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 770 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230390408-A1 | LINKER COMPOUNDS COMPRISING AMIDE BONDS | MPEG LA, L.L.C. | 2023-12-07 | — | — | US | claimed |
| CN-113717156-B | EGFR inhibitor, preparation method and application thereof | 南京红云生物科技有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-115916759-A | Substituted quinazoline compound, preparation method, pharmaceutical composition and application thereof | 南京红云生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115697996-A | Alkenyl pyrimidine compound, preparation method and application thereof | 南京红云生物科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-114728009-A | Preventing or treating diseases and disorders associated with tissue damage | 李晓祥 | 2022-07-08 | — | — | CN | claimed |
| WO-2021254464-A1 | SUBSTITUTED QUINAZOLINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 南京红云生物科技有限公司 | 2021-12-23 | — | — | WO | claimed |
| WO-2021238827-A1 | EGFR INHIBITOR AND PREPARATION METHOD AND USE THEREOF | 南京红云生物科技有限公司 | 2021-12-02 | — | — | WO | claimed |
| CN-113717156-A | EGFR inhibitor, preparation method and application thereof | 南京红云生物科技有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-109575045-B | Thienopyrimidine compound, preparation method thereof, medicinal composition and application thereof | 南京红云生物科技有限公司 | 2021-02-12 | — | — | CN | claimed |
| EP-3241829-B1 | HETEROARYLPIPERIDINE AND -PIPERAZINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2020-12-23 | — | — | EP | claimed |
| WO-1994011379-A1 | HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II ANTAGONISTS | ZENECA LIMITED (GB) | 1994-05-26 | — | — | WO | claimed |
| US-5294620-A | Hypotensive agents or compounds for cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-15 | — | — | US | claimed |
| WO-1994003453-A1 | PYRAZOLOPYRIDINE DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | ZENECA LIMITED (GB) | 1994-02-17 | — | — | WO | claimed |
| US-5217976-A | Hypotensive agents, congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-08 | — | — | US | claimed |
| US-5198439-A | Hypotensive agents, congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-30 | — | — | US | claimed |
| EP-0516392-A2 | Naphthyridine derivatives as angiotensin II inhibitors | ZENECA LIMITED (GB) | 1992-12-02 | — | — | EP | claimed |
| EP-0511791-A2 | Pyrrolopyridine derivatives as Angiotensin inhibitors | ZENECA LIMITED (GB) | 1992-11-04 | — | — | EP | claimed |
| EP-0453210-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | claimed |
| US-4981864-A | ANTICOAGULANTS | BOEHRINGER MANNEHIM GMBH (DE) | 1991-01-01 | — | — | US | claimed |
| EP-0209707-A2 | 2-Aryl imidazoles, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1987-01-28 | — | — | EP | claimed |