Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 17/20 | 0.55 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330497 | 0.87 | FPR2 (0.62) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2328578 | 0.85 | FPR2 (0.52) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2327605 | 0.84 | FPR2 (0.51) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2324631 | 0.84 | FPR2 (0.49) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL1167232 | 0.84 | HCRTR2 (0.58) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2327618 | 0.83 | FPR2 (0.53) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL27951819 | 0.83 | FPR2 (0.50) | FPR2 | |
| SCHEMBL2324536 | 0.82 | FPR2 (0.51) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2325147 | 0.82 | FPR2 (0.49) | FPR2HCRTR2HCRTR1 | |
| SCHEMBL2323231 | 0.81 | FPR2 (0.68) | FPR2HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | claimed |
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | disclosed |