Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23287655 | 0.87 | PIK3CD (0.45) | PIK3CDSRCPIK3R1PIK3R2PIK3CG | |
| SCHEMBL18518829 | 0.85 | SMN1; SMN2 (0.39) | PIK3CDSRCSMN1; SMN2LMNAHTT | |
| SCHEMBL18518266 | 0.81 | SRC (0.37) | PIK3CDSRCSMN1; SMN2LMNAHTT | |
| SCHEMBL23287653 | 0.80 | PIK3CD (0.41) | PIK3CD | |
| SCHEMBL18518582 | 0.79 | PIK3CD (0.36) | PIK3CDSRCSMN1; SMN2LMNAHTT | |
| SCHEMBL16005852 | 0.78 | PIK3CD (0.34) | PIK3CDLMNA | |
| SCHEMBL22243284 | 0.77 | EGFR (0.47) | PIK3CDLMNAHTTMAP4K4HSD17B10 | |
| SCHEMBL24671042 | 0.75 | CYP2C19 (0.36) | PIK3CDSRCSMN1; SMN2LMNAHTT | |
| SCHEMBL18518261 | 0.75 | RET (0.36) | PIK3CDSRCSMN1; SMN2LMNAHTT | |
| SCHEMBL25057478 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAHTTMAP4K4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3811974-A1 | TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS | Infinity Pharmaceuticals, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |