Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671954 | 0.80 | SRC (0.40) | SRCSMN1; SMN2PIK3CDBTKLMNA | |
| SCHEMBL13430257 | 0.77 | SRC (0.54) | SRCEGFRSMN1; SMN2SYKMAPT | |
| SCHEMBL24862167 | 0.75 | EGFR (0.53) | EGFRBTKHPGD | |
| SCHEMBL21082555 | 0.75 | SRC (0.35) | SRCSMN1; SMN2PIK3CDLMNAHTT | |
| SCHEMBL23287652 | 0.75 | PIK3CD (0.47) | SRCSMN1; SMN2PIK3CDALDH1A1HPGD | |
| SCHEMBL18518847 | 0.75 | RET (0.39) | SRCSMN1; SMN2PIK3CDALDH1A1HPGD | |
| SCHEMBL21501448 | 0.75 | PIK3CA (0.45) | SRCPIK3CDCYP1A2MAPTLMNA | |
| SCHEMBL18518829 | 0.74 | SMN1; SMN2 (0.39) | SRCSMN1; SMN2PIK3CDALDH1A1HPGD | |
| SCHEMBL22539865 | 0.74 | PIK3CA (0.42) | SRCSMN1; SMN2PIK3CDCYP3A4LMNA | |
| SCHEMBL8008751 | 0.74 | ALDH1A1 (0.42) | CYP2C19SMN1; SMN2PIK3CDALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043465-A1 | SUBSTITUTED AROMATIC FUSED RING DERIVATIVE AND COMPOSITION COMPRISING SAME, AND USE THEREOF | Shenzhen TargetRx, Inc. (CN) | 2022-08-17 | — | — | EP | disclosed |