Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.56 |
| ▸ | PRKDC | P78527 | 3/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | HCK | P08631 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884107 | 0.93 | PIK3CD (0.71) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL28395768 | 0.90 | PIK3CG (0.75) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9884084 | 0.90 | PIK3CG (0.70) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9884109 | 0.89 | PIK3CD (0.72) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9884111 | 0.88 | PIK3CG (0.77) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL955596 | 0.88 | PIK3CG (0.72) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL29479406 | 0.88 | PIK3CG (0.72) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9924613 | 0.86 | PIK3CG (0.76) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL13781706 | 0.86 | PIK3CG (0.76) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL19418809 | 0.86 | PIK3CD (0.77) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3811974-A1 | TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS | Infinity Pharmaceuticals, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |