Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 14/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16947002 | 0.88 | HDAC6 (0.37) | HDAC6HDAC1HDAC2CA14CPB2 | |
| SCHEMBL137000 | 0.85 | HDAC6 (0.46) | HDAC6HDAC1HDAC2CA14CPB2 | |
| SCHEMBL333215 | 0.82 | HDAC6 (0.38) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL3750380 | 0.82 | TDP1 (0.43) | HDAC6HDAC1HDAC2CA14CPB2 | |
| SCHEMBL21651913 | 0.82 | CA12 (0.40) | HDAC6HDAC1HDAC2CA14CPB2 | |
| SCHEMBL3882477 | 0.80 | HDAC6 (0.39) | HDAC6HDAC1HDAC2CA14CPB2 | |
| SCHEMBL14396847 | 0.80 | CA14 (0.41) | HDAC6HDAC1HDAC2CA14CPB2 | |
| SCHEMBL3750504 | 0.80 | CA14 (0.41) | HDAC6HDAC1HDAC2CA14CPB2 | |
| SCHEMBL13451787 | 0.80 | TDP1 (0.46) | HDAC6HDAC1HDAC2CA14CPB2 | |
| SCHEMBL21010750 | 0.78 | HDAC1 (0.41) | HDAC6HDAC1HDAC2CA14CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078132-A1 | INHIBITORS OF MTOR-MEDIATED INDUCTION OF AUTOPHAGY | SIRONAX LTD (GB) | 2021-04-29 | — | — | WO | disclosed |