SCHEMBL2328964

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2328957	1.00	KCNQ2 (0.49)	KCNQ2MAPTALDH1A1POLBMME
	SCHEMBL2328505	0.89	MME (0.49)	KCNQ2MAPTPOLBMMEHDAC3
	SCHEMBL2328501	0.89	MME (0.49)	KCNQ2MAPTPOLBMMEHDAC3
	SCHEMBL2328079	0.89	ALDH1A1 (0.49)	KCNQ2MAPTALDH1A1POLBMME
	SCHEMBL13583567	0.87	ALDH1A1 (0.47)	KCNQ2MAPTALDH1A1POLBCRHBP
	SCHEMBL13583561	0.87	ALDH1A1 (0.47)	KCNQ2MAPTALDH1A1POLBCRHBP
	SCHEMBL13583830	0.87	MME (0.54)	POLBMME
	SCHEMBL2330325	0.86	MME (0.49)	KCNQ2MAPTALDH1A1POLBMME
	SCHEMBL2327014	0.83	MME (0.49)	MME
	SCHEMBL2327018	0.83	MME (0.49)	MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.