Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.70 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PROC | P04070 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 6/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331531 | 0.89 | F10 (0.57) | F10PLGPROCF2PRSS1 | |
| SCHEMBL2332215 | 0.86 | F10 (0.52) | F10PLGPROCF2 | |
| SCHEMBL2330450 | 0.85 | F10 (0.69) | F10PLGPROCF2PRSS1 | |
| SCHEMBL2335132 | 0.83 | F10 (0.53) | F10PLGPROCF2 | |
| SCHEMBL2325190 | 0.82 | F10 (0.68) | F10PLGPROCF2 | |
| SCHEMBL2329162 | 0.81 | F10 (0.57) | F10PLGPROCF2 | |
| SCHEMBL2325323 | 0.81 | F10 (0.50) | F10PLGPROCF2 | |
| SCHEMBL2328805 | 0.80 | F10 (0.47) | F10PLGPROCF2PRSS1 | |
| SCHEMBL2328169 | 0.80 | F10 (0.70) | F10PLGPROCF2PRSS1 | |
| SCHEMBL2328900 | 0.80 | F10 (0.70) | F10PLGPROCF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-B1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2011-08-17 | — | — | EP | disclosed |
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |