⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188740 | 0.82 | — | — | |
| SCHEMBL2818716 | 0.79 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL3536369 | 0.78 | — | — | |
| SCHEMBL307841 | 0.77 | — | — | |
| SCHEMBL2812175 | 0.77 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL941453 | 0.77 | ALDH1A1 (0.47) | — | |
| SCHEMBL5875708 | 0.77 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL6292989 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL1908195 | 0.76 | — | — | |
| SCHEMBL2306049 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117023557-A | Preparation method and application of asphalt-based hard carbon composite material | 深圳钠博恩新材料有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-101670275-B | Preparation method for three-dimensional ordered macroporous chelating resin | UNIV HEBEI TECHNOLOGY | 2011-05-04 | — | — | CN | claimed |
| EP-1844044-B1 | THIAZOLE-4-CARBOXAMIDE DERIVATIVES AS MGLUR5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2010-07-21 | — | — | EP | claimed |
| CN-101670275-A | Preparation method for three-dimensional ordered macroporous chelating resin | UNIV HEBEI TECHNOLOGY | 2010-03-17 | — | — | CN | claimed |
| US-7678815-B2 | Thiazole-4-carboxyamide derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1844044-A1 | THIAZOLE-4-CARBOXAMIDE DERIVATIVES AS MGLUR5 ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-10-17 | — | — | EP | claimed |
| CN-101020687-A | New thiobizole formanide derivative and its synthesis process and bioactivity | UNIV NANKAI (CN) | 2007-08-22 | — | — | CN | claimed |
| US-20060160857-A1 | Thiazole-4-carboxyamide derivatives | HOFFMANN-LA ROCHE INC. | 2006-07-20 | — | — | US | claimed |
| WO-2006074884-A1 | THIAZOLE-4-CARBOXAMIDE DERIVATIVES AS MGLUR5 ANTAGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-07-20 | — | — | WO | claimed |
| JP-2006504796-A | — | — | 2006-02-09 | — | — | JP | claimed |
| EP-1551815-A1 | THIAZOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Pfizer Products Inc. (US) | 2005-07-13 | — | — | EP | claimed |
| US-20040152747-A1 | Thiazole compounds for treatment of neurodegenerative disorders | PFIZER INC | 2004-08-05 | — | — | US | claimed |
| WO-2004033439-A1 | THIAZOLE COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | PFIZER PRODUCTS INC. (US) | 2004-04-22 | — | — | WO | claimed |
| US-4719001-A | ALUMINUM COMPOUND AND THIADIAZOLE DERIVATIVE | UNION OIL COMPANY OF CALIFORNIA (US) | 1988-01-12 | — | — | US | claimed |
| US-12630562-B2 | Piperidylurea compounds and methods of use thereof | ARCUS BIOSCIENCES, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260042777-A1 | PIPERIDYLUREA COMPOUNDS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2026-02-12 | — | — | US | disclosed |
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED | 2026-01-08 | — | — | US | disclosed |
| EP-0002482-A1 | 4-Hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxides, processes for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-06-27 | — | — | EP | disclosed |
| US-4137313-A | ANTICOAGULANTS, ANTIPHLOGISTIC AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1979-01-30 | — | — | US | disclosed |
| US-3992535-A | ANTIINFLAMMATORY AGENTS, INHIBITORS OF PLATELET ADHESION AND AGGREGATION | BOEHRINGER INGELHEIM GMBH (DT) | 1976-11-16 | — | — | US | disclosed |