Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.72 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTR3A | P46098 | 1/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143553 | 0.97 | GFER (0.77) | GFERLOXL2TAAR1MAOBHTR2A | |
| Ammonia Solution, Strong SCHEMBL28618283 | 0.94 | GFER (0.72) | GFERLOXL2TAAR1MAOBHTR2A | |
| Hydrochloric Acid SCHEMBL3175945 | 0.94 | GFER (0.72) | GFERLOXL2TAAR1MAOBHTR2A | |
| Hydrochloric Acid SCHEMBL1879353 | 0.94 | GFER (0.72) | GFERLOXL2TAAR1MAOBHTR2A | |
| Ethane SCHEMBL23291175 | 0.92 | GFER (0.68) | GFERLOXL2TAAR1MAOBHTR2A | |
| SCHEMBL17154336 | 0.89 | ALDH1A1 (0.74) | GFERLOXL2TAAR1MAOBHTR2A | |
| SCHEMBL16544040 | 0.89 | GFER (0.65) | GFERLOXL2TAAR1MAOBHTR2A | |
| SCHEMBL224548 | 0.87 | TAAR1 (0.72) | GFERLOXL2TAAR1MAOBHTR2A | |
| SCHEMBL8356905 | 0.85 | TAAR1 (0.86) | GFERLOXL2TAAR1MAOBHTR2A | |
| Hydrochloric Acid SCHEMBL3168355 | 0.84 | BLM (0.74) | GFERLOXL2TAAR1MAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814356-A1 | TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS | Zhejiang Vimgreen Pharmaceuticals, Ltd (CN) | 2021-05-05 | — | — | EP | disclosed |