Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24630462 | 0.78 | HRH3 (0.42) | HRH3 | |
| SCHEMBL21725673 | 0.78 | — | — | |
| SCHEMBL3477460 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2HSD11B1HRH3 | |
| SCHEMBL21013066 | 0.74 | MEN1 (0.30) | SMN1; SMN2 | |
| SCHEMBL3476998 | 0.74 | HSD11B1 (0.55) | SMN1; SMN2HSD11B1HRH3 | |
| SCHEMBL22764417 | 0.73 | ATM (0.33) | — | |
| SCHEMBL22224660 | 0.73 | SMN1; SMN2 (0.36) | SMN1; SMN2HSD11B1HRH3 | |
| SCHEMBL10660547 | 0.73 | MEN1 (0.36) | SMN1; SMN2 | |
| SCHEMBL21725692 | 0.72 | — | — | |
| SCHEMBL8226927 | 0.71 | SMN1; SMN2 (0.45) | SMN1; SMN2HSD11B1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022126000-A1 | METHODS AND COMPOUNDS FOR MODULATING MYOTONIC DYSTROPHY 1 | Design Therapeutics, Inc. (US) | 2022-06-16 | — | — | WO | disclosed |
| EP-3812387-A1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | Sumitomo Dainippon Pharma Oncology, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |