Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26239731 | 0.82 | CA1 (0.35) | KMT2ACA1ALDH1A1ALOX15BLM | |
| SCHEMBL3187223 | 0.81 | FFAR3 (0.44) | FDPSKMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL1686729 | 0.76 | FDPS (0.42) | FDPSKMT2AMEN1CA12CA1 | |
| SCHEMBL23743650 | 0.74 | FDPS (0.40) | FDPSCA12CA1CA2CA14 | |
| SCHEMBL27010013 | 0.73 | FDPS (0.36) | FDPSCA12CA2ALDH1A1HPGD | |
| SCHEMBL3871273 | 0.73 | CA12 (0.41) | SOAT1KMT2AMEN1FAAHTP53 | |
| SCHEMBL2835999 | 0.73 | KMT2A (0.40) | SOAT1KMT2AMEN1FAAHTP53 | |
| SCHEMBL10333911 | 0.73 | CA12 (0.41) | SOAT1KMT2AMEN1FAAHTP53 | |
| SCHEMBL6050210 | 0.72 | FDPS (0.39) | FDPSCA12CA2CA9 | |
| SCHEMBL6464153 | 0.72 | KMT2A (0.36) | FDPSSOAT1KMT2AMEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812387-A1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | Sumitomo Dainippon Pharma Oncology, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |