Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 19/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.81 |
| ▸ | FYN | P06241 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103197 | 0.89 | PIM1 (1.00) | PIM1KCNH2 | |
| SCHEMBL138855 | 0.89 | PIM1 (1.00) | PIM1KCNH2 | |
| SCHEMBL103173 | 0.89 | PIM1 (1.00) | PIM1KCNH2 | |
| SCHEMBL19986988 | 0.89 | PIM1 (0.84) | PIM1KCNH2 | |
| SCHEMBL19986920 | 0.88 | PIM1 (0.82) | PIM1KCNH2 | |
| SCHEMBL14638741 | 0.88 | PIM1 (1.00) | PIM1KCNH2 | |
| SCHEMBL102689 | 0.88 | PIM1 (1.00) | PIM1KCNH2FYN | |
| SCHEMBL103260 | 0.88 | PIM1 (1.00) | PIM1KCNH2 | |
| SCHEMBL19986912 | 0.88 | PIM1 (0.82) | PIM1KCNH2 | |
| SCHEMBL102171 | 0.87 | PIM1 (1.00) | PIM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812387-A1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | Sumitomo Dainippon Pharma Oncology, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |