SCHEMBL23299352

SCHEMBL23299352

CC(C)c1cccc(C(C)C)c1OC(=O)COC(=O)[C@H](N)CO

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SCN5A Q14524 1/20 0.43
SCN9A Q15858 1/20 0.43
SCN10A Q9Y5Y9 1/20 0.43
NLRP3 Q96P20 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23299369 0.88 SCN5A (0.42) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299332 0.88 SCN5A (0.42) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299338 0.88 SCN5A (0.42) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299310 0.87 SCN5A (0.46) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299312 0.87 SCN5A (0.46) SCN5ASCN9ASCN10ANLRP3
SCHEMBL28482983 0.87 SCN5A (0.48) SCN5ASCN9ASCN10A
SCHEMBL23299368 0.86 SCN5A (0.41) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299327 0.84 SCN5A (0.44) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299328 0.84 SCN5A (0.44) SCN5ASCN9ASCN10ANLRP3
SCHEMBL23299351 0.84 ALPI (0.44) SCN5ASCN9ASCN10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220388947-A1 Nitrogen-containing Derivative of Substituted Phenol Hydroxy Acid Ester, and Preparation and Use Thereof WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) 2022-12-08 US disclosed
WO-2021078073-A1 N-CONTAINING DERIVATIVE OF SUBSTITUTED PHENOL HYDROXY ACID ESTER, AND PREPARATION AND USE THEREOF 四川大学华西医院 2021-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388947-A1 Nitrogen-containing Derivative of Substituted Phenol Hydroxy Acid Ester, and Preparation and Use Thereof EGLN2, EGLN3, HPD SCN5A 788/4885SCN9A 513/4885SCN10A 463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.