Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23299367 | 1.00 | SCN5A (0.38) | SCN5ASCN9ASCN10ASCN4ANLRP3 | |
| SCHEMBL23299333 | 0.97 | SLC6A3 (0.39) | — | |
| SCHEMBL10241519 | 0.86 | SCN4A (0.43) | SCN5ASCN9ASCN10ASCN4ACYP1A2 | |
| SCHEMBL2677256 | 0.86 | SCN4A (0.43) | SCN5ASCN9ASCN10ASCN4ACYP1A2 | |
| Hydrochloric Acid SCHEMBL6260458 | 0.85 | SCN4A (0.42) | SCN5ASCN9ASCN10ASCN4ACYP1A2 | |
| SCHEMBL23299335 | 0.83 | SLC18A2 (0.36) | SCN5ASCN9ASCN10ANLRP3 | |
| SCHEMBL24740674 | 0.82 | TDP1 (0.43) | SCN5ASCN9ASCN10ANLRP3 | |
| SCHEMBL17551731 | 0.78 | SCN4A (0.35) | SCN4ACYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3160590 | 0.77 | PRCP (0.48) | — | |
| SCHEMBL17598343 | 0.76 | SCN4A (0.34) | SCN4ACYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078073-A1 | N-CONTAINING DERIVATIVE OF SUBSTITUTED PHENOL HYDROXY ACID ESTER, AND PREPARATION AND USE THEREOF | 四川大学华西医院 | 2021-04-29 | — | — | WO | disclosed |