SCHEMBL23299454

SCHEMBL23299454

CC1(C)C2=CC=CCC2Oc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.31
AKR1B1 P15121 1/20 0.31
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
AR P10275 1/20 0.30
CYP19A1 P11511 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7612604 0.69 BRD4 (0.40)
SCHEMBL20880987 0.67 PDK2 (0.38) NPC1MAPTRAB9AKDM4E
SCHEMBL12194864 0.66 MAOB (0.41) MAOBNPC1MAPTRAB9AKDM4E
SCHEMBL24489433 0.66 NISCH (0.33) MAOBNPC1MAPTRAB9AKDM4E
SCHEMBL22289339 0.65 DRD1 (0.31)
SCHEMBL18211740 0.65 MAOB (0.44) MAOBAKR1B1KDM4EADORA3AR
SCHEMBL18403517 0.64 MAOB (0.38) MAOBKDM4EADORA3ARCYP19A1
SCHEMBL20991574 0.63
SCHEMBL8002252 0.60 DRD2 (0.40) AKR1B1MAPTKDM4EHSD17B10
SCHEMBL9327109 0.60 POLB (0.55) AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3415512-B1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING SAME LG CHEMICAL LTD (KR) 2021-04-28 EP disclosed