SCHEMBL23299563

SCHEMBL23299563

c1ccc(-c2nc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)nc(-c3ccc4c(c3)sc3cccc(-c5ccccc5)c34)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LIMK1 P53667 1/20 0.33
F9 P00740 1/20 0.32
MAPK14 Q16539 1/20 0.31
PDE1B Q01064 1/20 0.31
PDE3A Q14432 1/20 0.31
PDE11A Q9HCR9 1/20 0.31
HDAC4 P56524 1/20 0.31
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30
RXRA P19793 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22329943 0.96 KDM4E (0.36) KDM4EATML3MBTL1F9PDE1B
SCHEMBL25965530 0.95 KDM4E (0.35) KDM4EATML3MBTL1LIMK1PDE1B
SCHEMBL22257888 0.95 KDM4E (0.34) KDM4EATML3MBTL1LIMK1HDAC4
SCHEMBL25965515 0.94 KDM4E (0.33) KDM4EATML3MBTL1LIMK1F9
SCHEMBL22257661 0.94 KDM4E (0.33) KDM4EATML3MBTL1LIMK1HDAC4
SCHEMBL22258147 0.94 KDM4E (0.38) KDM4EATML3MBTL1LIMK1PDE1B
SCHEMBL25928679 0.94 KDM4E (0.32) KDM4EATML3MBTL1LIMK1
SCHEMBL25928629 0.94 KDM4E (0.32) KDM4EATML3MBTL1LIMK1
SCHEMBL25928693 0.94 KDM4E (0.33) KDM4EATML3MBTL1F9ADORA2A
SCHEMBL22258153 0.93 KDM4E (0.35) KDM4EATML3MBTL1LIMK1PDE1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021080368-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-04-29 WO disclosed