Acetic Acid

Acetic Acid

SCHEMBL233000

CC(=O)O.O=c1ccc2nc3ccc(O)cc3oc-2c1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 known ✓ P03372 3/20 0.42
ESR2 known ✓ Q92731 3/20 0.42
APP P05067 13/20 0.86
CYP1A2 P05177 1/20 0.56
USP2 O75604 2/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
PLEC Q15149 1/20 0.42
SNCA P37840 1/20 0.42
PDE4D Q08499 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8066 0.93 APP (1.00) APPCYP1A2USP2MEN1POLB
SCHEMBL29456578 0.92 APP (0.97) APPCYP1A2USP2MEN1POLB
SCHEMBL7113427 0.92 APP (0.97) APPCYP1A2USP2MEN1POLB
Ammonia Solution, Strong SCHEMBL29419058 0.92 APP (0.97) APPCYP1A2USP2MEN1POLB
SCHEMBL1095367 0.92 APP (0.97) APPCYP1A2USP2MEN1POLB
Propionic Acid SCHEMBL21043899 0.91 APP (0.80) APPCYP1A2USP2MEN1POLB
SCHEMBL6813574 0.91 APP (0.80) APPCYP1A2USP2MEN1POLB
Propionic Acid SCHEMBL21043901 0.91 APP (0.80) APPCYP1A2USP2MEN1POLB
Methoxymethane SCHEMBL2784008 0.90 APP (0.89) APPCYP1A2USP2MEN1POLB
Levulinic Acid SCHEMBL8512310 0.89 APP (0.73) APPCYP1A2USP2MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230184763-A1 METHOD OF DETECTING VIRUS HAVING HEMAGGLUTININ-ESTERASE ACTIVITY LEE JI HOON (US) 2023-06-15 US claimed
CN-115298548-A Method for detecting viruses having hemagglutinin esterase activity 李知勋 2022-11-04 CN claimed
US-9850522-B2 One-step rapid assay for the detection of inhibitors of enzymes ANP TECHNOLOGIES, INC. (US) 2017-12-26 US claimed
WO-2017100703-A1 EMS ANALOGUES OF LYN/SRC-TYROSINE KINASE INHIBITORS COMBS COLIN (US) 2017-06-15 WO claimed
US-9631219-B2 Metabolic rate indicator for cellular populations NALCO COMPANY (US) 2017-04-25 US claimed
US-20150368691-A1 One-step Rapid Assay for the Detection of Inhibitors of Enzymes FULGENT GENETICS, INC. 2015-12-24 US claimed
US-8097404-B2 Composition and method for cell permeabilization comprising N-octyl-β-D-glucopyranoside, sodium polyphosphates, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORPORATION (US) 2012-01-17 US claimed
EP-2107119-B1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2010-05-12 EP claimed
EP-2107119-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane Millipore Corporation (US) 2009-10-07 EP claimed
US-20090246822-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane EMD MILLIPORE CORPORATION 2009-10-01 US claimed
US-6806089-B1 QUANTITATIVE ANALYSIS; DOES NOT REQUIRE THE SENSING FLUOROPHORE TO DISPLAY A CHANGE IN LIFETIME; SELF-CALIBRATING UNIVERSITY OF MARYLAND, BALTIMORE 2004-10-19 US claimed
WO-2000014515-A9 LOW FREQUENCY MODULATION SENSORS USING NANOSECOND FLUOROPHORES UNIV MARYLAND (US) 2000-08-31 WO claimed
WO-2000014515-A1 LOW FREQUENCY MODULATION SENSORS USING NANOSECOND FLUOROPHORES UNIVERSITY OF MARYLAND AT BALTIMORE (US) 2000-03-16 WO claimed
US-12385917-B2 Methods and compositions for tracking vegetation COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2025-08-12 US disclosed
EP-4594521-A2 METHODS AND SYSTEMS FOR GENE MUTAGENESIS President and Fellows of Harvard College (US) 2025-08-06 EP disclosed
EP-4594516-A2 SYSTEMS AND METHODS FOR SCREENING OF LARGE GENE LIBRARIES President and Fellows of Harvard College (US) 2025-08-06 EP disclosed
EP-0694164-A4 METHOD FOR OPTICALLY MEASURING CHEMICAL ANALYTES UNIV MARYLAND (US) 1994-06-22 EP disclosed
WO-1993010460-A1 INDIRECT IMMUNOASSAY FOR DIOXINLIKE COMPOUNDS CORNELL RESEARCH FOUNDATION, INC. (US) 1993-05-27 WO disclosed
WO-1992019957-A2 METHOD FOR OPTICALLY MEASURING CHEMICAL ANALYTES UNIVERSITY OF MARYLAND AT BALTIMORE (US) 1992-11-12 WO disclosed
US-4716222-A CHROMOGENS, SPECTROPHOTOMETRY HOECHST AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed