Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 14/20 | 0.40 |
| ▸ | CTSS | P25774 | 9/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23314623 | 0.82 | CA1 (0.42) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL6291038 | 0.82 | CA1 (0.42) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL29548346 | 0.82 | CA1 (0.42) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL23300003 | 0.82 | CA1 (0.42) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL6291036 | 0.82 | CA1 (0.42) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL19056015 | 0.81 | CA12 (0.41) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL14842381 | 0.80 | CA1 (0.43) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL22567184 | 0.76 | CA1 (0.46) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL24812376 | 0.76 | CTSK (0.44) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL22852330 | 0.76 | CA1 (0.41) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081375-A1 | INHIBITORS OF RAF KINASES | KINNATE BIOPHARMA INC. (US) | 2021-04-29 | — | — | WO | disclosed |