Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.68 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23538836 | 1.00 | DDB1 (0.68) | DDB1CRBNS1PR1ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL30147971 | 0.94 | DDB1 (0.61) | DDB1CRBNS1PR1ITGB3ITGA2B | |
| SCHEMBL23301551 | 0.86 | DDB1 (0.64) | DDB1CRBNDRD2DRD4DRD3 | |
| SCHEMBL29744852 | 0.86 | DDB1 (0.64) | DDB1CRBNDRD2DRD4DRD3 | |
| SCHEMBL23551746 | 0.86 | DDB1 (0.64) | DDB1CRBNDRD2DRD4DRD3 | |
| SCHEMBL23538927 | 0.85 | DDB1 (0.72) | DDB1CRBN | |
| SCHEMBL24124617 | 0.84 | DDB1 (0.54) | DDB1CRBNS1PR1 | |
| SCHEMBL25167579 | 0.84 | DDB1 (0.54) | DDB1CRBNS1PR1 | |
| SCHEMBL24125956 | 0.84 | DDB1 (0.54) | DDB1CRBNS1PR1 | |
| Hydrochloric Acid SCHEMBL23301328 | 0.83 | DDB1 (0.53) | DDB1CRBNS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051674-A1 | BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2022-09-07 | — | — | EP | disclosed |
| WO-2021083949-A1 | BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2021-05-06 | — | — | WO | disclosed |