Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29744852 | 1.00 | DDB1 (0.64) | DDB1CRBNDRD2DRD4DRD3 | |
| SCHEMBL23551746 | 1.00 | DDB1 (0.64) | DDB1CRBNDRD2DRD4DRD3 | |
| SCHEMBL23301396 | 0.86 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL25173024 | 0.86 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL25168320 | 0.86 | DDB1 (0.52) | DDB1CRBN | |
| SCHEMBL23301404 | 0.86 | DDB1 (0.68) | DDB1CRBNDRD2DRD4DRD3 | |
| SCHEMBL23538836 | 0.86 | DDB1 (0.68) | DDB1CRBNDRD2DRD4DRD3 | |
| SCHEMBL20595415 | 0.85 | DDB1 (0.74) | DDB1CRBN | |
| SCHEMBL21903077 | 0.85 | DDB1 (0.74) | DDB1CRBN | |
| SCHEMBL29744797 | 0.85 | DDB1 (0.74) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051674-A1 | BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2022-09-07 | — | — | EP | disclosed |
| WO-2021083949-A1 | BIFUNCTIONAL COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2021-05-06 | — | — | WO | disclosed |