SCHEMBL233023

SCHEMBL233023

CCOC(=O)C1CCC(C)CC1C(=O)OCC

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 1/20 0.50
PPM1B O75688 1/20 0.41
PTPN1 P18031 1/20 0.41
PPP1CC P36873 1/20 0.41
MAPT P10636 3/20 0.40
EPHX1 P07099 1/20 0.39
CA1 P00915 5/20 0.39
CA2 P00918 5/20 0.39
CA12 O43570 4/20 0.39
CA9 Q16790 3/20 0.39
PKM P14618 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18828251 1.00 TRPM8 (0.50) TRPM8PPM1BPTPN1PPP1CCMAPT
SCHEMBL14189736 1.00 TRPM8 (0.50) TRPM8PPM1BPTPN1PPP1CCMAPT
SCHEMBL14189731 1.00 TRPM8 (0.50) TRPM8PPM1BPTPN1PPP1CCMAPT
SCHEMBL20073034 1.00 TRPM8 (0.50) TRPM8PPM1BPTPN1PPP1CCMAPT
SCHEMBL17852174 0.93 TRPM8 (0.46) TRPM8PPM1BPTPN1PPP1CCMAPT
SCHEMBL1196048 0.90 TRPM8 (0.43) TRPM8PPM1BPTPN1PPP1CCMAPT
SCHEMBL14465136 0.90 TRPM8 (0.47) TRPM8PPM1BPTPN1PPP1CCMAPT
SCHEMBL18828250 0.90 TRPM8 (0.47) TRPM8PPM1BPTPN1PPP1CCMAPT
SCHEMBL14465134 0.89 TRPM8 (0.43) TRPM8PPM1BPTPN1PPP1CCMAPT
SCHEMBL1196053 0.89 TRPM8 (0.42) TRPM8PPM1BPTPN1PPP1CCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397658-B1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA INC (US) 2022-07-27 EP claimed
US-11117982-B2 Non-phthalate catalyst system and its use in the polymerization of olefins BRASKEM AMERICA, INC. (US) 2021-09-14 US claimed
US-20190016832-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. (US) 2019-01-17 US claimed
EP-3397658-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS Braskem America, Inc. (US) 2018-11-07 EP claimed
WO-2017117439-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. (US) 2017-07-06 WO claimed
EP-3397658-B1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA INC (US) 2022-07-27 EP disclosed
EP-2876118-B1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO LTD (JP) 2022-04-06 EP disclosed
US-11117982-B2 Non-phthalate catalyst system and its use in the polymerization of olefins BRASKEM AMERICA, INC. (US) 2021-09-14 US disclosed
US-11041028-B2 Non-phthalate catalyst system and its use in the polymerization of olefins BRASKEM AMERICA, INC. (US) 2021-06-22 US disclosed
US-20200199262-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. 2020-06-25 US disclosed
US-10633464-B2 Non-phthalate catalyst system and its use in the polymerization of olefins BRASKEM AMERICA, INC. (US) 2020-04-28 US disclosed
US-10633463-B2 Non-phthalate catalyst system and its use in the polymerization of olefins BRASKEM AMERICA, INC. (US) 2020-04-28 US disclosed
US-20080113860-A1 Solid phase hydrocarbon-insoluble catalyst component; magnesium, titanium, and halogen; aluminum alkyl; internal electron donor; bicyclo structure; propylene polymers BP CORPORATION NORTH AMERICA INC. (US) 2008-05-15 US disclosed
US-20080113860-A1 Solid phase hydrocarbon-insoluble catalyst component; magnesium, titanium, and halogen; aluminum alkyl; internal electron donor; bicyclo structure; propylene polymers BP CORPORATION NORTH AMERICA INC. (US) 2008-05-15 US disclosed
US-20080097050-A1 Solid titanium catalyst component, catalyst for polymerization of olefin and process for producing olefin polymer MITSUI CHEMICALS, INC. (JP) 2008-04-24 US disclosed
EP-1845113-A1 SOLID TITANIUM CATALYST COMPONENT, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER Mitsui Chemicals, Inc. (JP) 2007-10-17 EP disclosed
US-7282601-B2 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester NEW JAPAN CHEMICAL CO., LTD. (JP) 2007-10-16 US disclosed
US-7271282-B1 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester NEW JAPAN CHEMICAL CO., LTD. (JP) 2007-09-18 US disclosed
US-20050038283-A1 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester NEW JAPAN CHEMICAL, CO., LTD. (JP) 2005-02-17 US disclosed
EP-1227078-A1 DICARBOXYLIC DIESTER, PROCESS FOR PRODUCING THE SAME, AND REFRIGERATING MACHINE LUBRICATING OIL COMPRISING THE ESTER NEW JAPAN CHEMICAL CO.,LTD. (JP) 2002-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038283-A1 Dicarboxylic diester, process for producing the same, and refrigerating machine lubricating oil comprising the ester SCO2, PDHX, DECR2 TRPM8 2218/4885PPM1B 3735/4885PTPN1 3564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.