Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK6 | Q92876 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 5/20 | 0.40 |
| ▸ | F10 | P00742 | 5/20 | 0.40 |
| ▸ | FNTA | P49354 | 9/20 | 0.39 |
| ▸ | FNTB | P49356 | 9/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PROC | P04070 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331807 | 0.88 | F10 (0.39) | KLK6F2F10FNTAFNTB | |
| SCHEMBL7475980 | 0.87 | F10 (0.35) | KLK6F2F10FNTAFNTB | |
| SCHEMBL2329584 | 0.87 | FNTA (0.44) | KLK6F2F10FNTAFNTB | |
| SCHEMBL2330020 | 0.86 | MAPT (0.36) | F2F10FNTAFNTBPGGT1B | |
| SCHEMBL2326867 | 0.82 | F10 (0.35) | KLK6F2F10FNTAFNTB | |
| SCHEMBL2328755 | 0.81 | F10 (0.45) | KLK6F2F10FNTAFNTB | |
| Trifluoroacetic Acid SCHEMBL2333940 | 0.80 | KLK6 (0.49) | KLK6F2F10PLGPLAT | |
| Trifluoroacetic Acid SCHEMBL2333936 | 0.80 | KLK6 (0.49) | KLK6F2F10PLGPLAT | |
| SCHEMBL8425396 | 0.78 | FNTA (0.43) | F2F10FNTAFNTBPGGT1B | |
| SCHEMBL2330362 | 0.78 | F10 (0.68) | KLK6F2F10PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-B1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2011-08-17 | — | — | EP | disclosed |
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |