Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330020 | 0.93 | MAPT (0.36) | F10CTSLCTSSF2GAA | |
| SCHEMBL2331807 | 0.88 | F10 (0.39) | F10F2KLK6FNTAFNTB | |
| SCHEMBL2330347 | 0.87 | KLK6 (0.41) | F10F2KLK6FNTAFNTB | |
| Trifluoroacetic Acid SCHEMBL7421384 | 0.83 | F2 (0.42) | F10F2KLK6 | |
| SCHEMBL2326867 | 0.83 | F10 (0.35) | F10F2KLK6FNTAFNTB | |
| SCHEMBL2329422 | 0.80 | F10 (0.59) | F10F2KLK6 | |
| SCHEMBL8425396 | 0.79 | FNTA (0.43) | F10F2FNTAFNTBPGGT1B | |
| Trifluoroacetic Acid SCHEMBL2333125 | 0.77 | F10 (0.41) | F10F2KLK6MAPT | |
| SCHEMBL2329584 | 0.75 | FNTA (0.44) | F10F2KLK6FNTAFNTB | |
| SCHEMBL8424475 | 0.74 | GAA (0.35) | F10F2GAATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996040679-A1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-12-19 | — | — | WO | disclosed |