SCHEMBL233046

SCHEMBL233046

CCCCCCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 1.00
NR5A2 O00482 1/20 1.00
NR5A1 Q13285 1/20 1.00
MAPT P10636 3/20 0.88
FABP3 P05413 1/20 0.78
RECQL P46063 1/20 0.77
ALDH1A1 P00352 1/20 0.68
ADRA1D P25100 1/20 0.66
PTAFR P25105 1/20 0.66
HTR1D P28221 1/20 0.66
HTR2C P28335 1/20 0.66
ADRA1B P35368 1/20 0.66
DRD3 P35462 1/20 0.66
TMEM97 Q5BJF2 1/20 0.66
LPAR3 Q9UBY5 3/20 0.63
LPAR1 Q92633 2/20 0.63
ENPP2 Q13822 1/20 0.63
MAPK1 P28482 3/20 0.60
MEN1 O00255 2/20 0.60
GMNN O75496 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimyristoylphosphatidylcholine SCHEMBL244839 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL10498112 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
Dimyristoylphosphatidylcholine SCHEMBL37475 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL234790 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL22693933 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
Dimyristoylphosphatidylcholine SCHEMBL236969 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL231824 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL2036043 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
SCHEMBL24563 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3
Colfosceril Palmitate SCHEMBL2734250 1.00 SMN1; SMN2 (1.00) SMN1; SMN2NR5A2NR5A1MAPTFABP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4712950-A2 IONIZABLE AMINE LIPIDS Intellia Therapeutics, Inc. (US) 2026-03-25 EP claimed
EP-4706644-A1 RECONSTITUTED HIGH-DENSITY LIPOPROTEIN NANOPARTICLES COMPRISING CHOLESTEROL Mepsgen Co., Ltd. (KR) 2026-03-11 EP claimed
EP-4665314-A1 LIPID NANOPARTICLE CONTAINING PORPHYRIN FOR THE DELIVERY OF RNA University Health Network (CA) 2025-12-24 EP claimed
WO-2025226857-A2 COMPOSITIONS AND METHODS FOR TREATING HYPOXIA-RELATED CONDITIONS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-10-30 WO claimed
WO-2025132906-A1 FOCUSED ULTRASOUND THERMAL ABLATION WITH THERMAL ENHANCERS BRACCO SUISSE SA (CH) 2025-06-26 WO claimed
US-20250177503-A1 COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-06-05 US claimed
EP-4482511-A2 COMPOSITIONS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS The Regents of The University of Michigan (US) 2025-01-01 EP claimed
WO-2024243031-A2 IONIZABLE AMINE LIPIDS INTELLIA THERAPEUTICS, INC. (US) 2024-11-28 WO claimed
US-20240382626-A1 IRRADIATION AMENABLE LIPOSOMAL DYE AGGREGATES AND METHODS OF SYNTHESIS AND USE THEREOF UNIV TEXAS (US) 2024-11-21 US claimed
WO-2024168439-A1 LIPID NANOPARTICLE CONTAINING PORPHYRIN FOR THE DELIVERY OF RNA UNIVERSITY HEALTH NETWORK (CA) 2024-08-22 WO claimed
US-20130177637-A1 METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES PACIRA PHARMACEUTICALS, INC. (US) 2013-07-11 US claimed
US-20110250264-A1 METHOD FOR FORMULATING LARGE DIAMETER SYNTHETIC MEMBRANE VESICLES PACIRA PHARMACEUTICALS, INC. (US) 2011-10-13 US claimed
EP-2322143-A1 Method for utilizing neutral lipids to modify in vivo release from multivesicular liposomes Pacira Pharmaceuticals, Inc. (US) 2011-05-18 EP claimed
US-20090092661-A1 LIPOSOME COMPOSITIONS FOR IN VIVO ADMINISTRATION OF BORONIC ACID COMPOUNDS ALZA CORPORATION 2009-04-09 US claimed
EP-0971699-A4 METHOD FOR UTILIZING NEUTRAL LIPIDS TO MODIFY IN VIVO RELEASE FROM MULTIVESICULAR LIPOSOMES SKYEPHARMA INC (US) 2006-05-24 EP claimed
US-6241999-B1 SUBSTITUTING FIRST AMPHIPATHIC LIPID WITH ONE HAVING A SIMILIAR STRUCTURE BUT MORE C ATOMS SKYEPHARMA, INC. 2001-06-05 US claimed
US-6193998-B1 INCREASING EFFICIENCY USING MULTIVESICULAR LIPOSOMES CONTAINING PHOSPHOLIPIDS SKYEPHARMA INC. 2001-02-27 US claimed
US-6171613-B1 REPLACING AMPHIPATHIC LIPIDS SKYEPHARMA INC. 2001-01-09 US claimed
EP-0971699-A1 METHOD FOR UTILIZING NEUTRAL LIPIDS TO MODIFY IN VIVO RELEASE FROM MULTIVESICULAR LIPOSOMES SkyePharma Inc. (US) 2000-01-19 EP claimed
WO-1998033483-A1 METHOD FOR UTILIZING NEUTRAL LIPIDS TO MODIFY IN VIVO RELEASE FROM MULTIVESICULAR LIPOSOMES SKYEPHARMA, INC. (US) 1998-08-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090092661-A1 LIPOSOME COMPOSITIONS FOR IN VIVO ADMINISTRATION OF BORONIC ACID COMPOUNDS LIPA, LPAR6, ABHD6 SMN1; SMN2 388/4885NR5A2 4575/4885NR5A1 4472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.