Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15455713 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TDP1TRPA1LMNASLC15A2 | |
| SCHEMBL4342888 | 0.97 | ALDH1A1 (0.50) | ALDH1A1TDP1TRPA1LMNASLC15A2 | |
| SCHEMBL11309347 | 0.88 | TDP1 (0.48) | ALDH1A1TDP1TRPA1LMNASLC15A2 | |
| SCHEMBL11848040 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1TRPA1 | |
| SCHEMBL24834180 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TDP1 | |
| SCHEMBL2010639 | 0.80 | TDP1 (0.53) | ALDH1A1TDP1TRPA1LMNASLC15A2 | |
| SCHEMBL11848055 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL25457592 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL517199 | 0.78 | SLC22A6 (0.45) | ALDH1A1TDP1LMNASLC15A2 | |
| SCHEMBL15658158 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408730-B1 | PROCESS FOR THE CATALYTIC HALOGENATION OF A DIOL | AKZO NOBEL NV (NL) | 2015-07-01 | — | — | EP | claimed |
| US-8558021-B2 | Process for the catalytic halogenation of a diol | AKZO NOBEL N.V. (NL) | 2013-10-15 | — | — | US | claimed |
| US-20120004432-A1 | PROCESS FOR THE CATALYTIC HALOGENATION OF A DIOL | AKZO NOBEL N.V. (NL) | 2012-01-05 | — | — | US | claimed |
| EP-3206720-B1 | CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES | SCV GMBH (DE) | 2020-04-22 | — | — | EP | disclosed |
| EP-3206720-A1 | CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES | SCV GmbH (DE) | 2017-08-23 | — | — | EP | disclosed |
| WO-2016058704-A1 | CONJUGATED BISPHOSPHONATES FOR THE DIAGNOSIS AND THERAPY OF BONE DISEASES | SCV GMBH (DE) | 2016-04-21 | — | — | WO | disclosed |
| EP-2763944-B1 | PROCESS FOR THE CHLORINATION OF A HYDROXYLATED ORGANIC COMPOUND | AKZO NOBEL CHEMICALS INT BV (NL) | 2015-12-16 | — | — | EP | disclosed |
| EP-2408730-B1 | PROCESS FOR THE CATALYTIC HALOGENATION OF A DIOL | AKZO NOBEL NV (NL) | 2015-07-01 | — | — | EP | disclosed |
| US-9006498-B2 | Process for the chlorination of a hydroxylated organic compound | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2015-04-14 | — | — | US | disclosed |
| US-20140371492-A1 | PROCESS FOR THE CHLORINATION OF A HYDROXYLATED ORGANIC COMPOUND | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2014-12-18 | — | — | US | disclosed |
| US-8759348-B2 | Use of 4-(pyrrolidin-1-yl)quinoline compounds to kill clinically latent microorganisms | HELPERBY THERAPEUTICS LIMITED (GB) | 2014-06-24 | — | — | US | disclosed |
| WO-2010101560-A1 | BIS[(ALKYLAMINO)ALKYL]AMINES | ALBEMARLE CORPORATION (US) | 2010-09-10 | — | — | WO | disclosed |
| US-20100160392-A1 | HISTONE DEACETYLASE INHIBITORS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2010-06-24 | — | — | US | disclosed |
| US-20090030099-A1 | FOAM COMPOSITION AND FOAM | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| WO-2008130721-A1 | PREPARATION OF SECONDARY DIAMINES | ALBEMARLE CORPORATION (US) | 2008-10-30 | — | — | WO | disclosed |
| EP-0679640-B1 | Carboxylate and heat-sensitive recording material using same | MITSUI CHEMICALS INC (JP) | 2001-08-08 | — | — | EP | disclosed |
| US-5691272-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5559247-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-09-24 | — | — | US | disclosed |
| CN-1114431-A | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS (JP) | 1996-01-03 | — | — | CN | disclosed |
| EP-0679640-A1 | Carboxylate and heat-sensitive recording material using same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160392-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC4 | ALDH1A1 2757/4885TDP1 3241/4885TRPA1 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.