Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 4/20 | 0.41 |
| ▸ | CDK8 | P49336 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330579 | 1.00 | DPP4 (0.44) | DPP4ALDH1A1MAPTP2RX3TTR | |
| SCHEMBL30836979 | 0.86 | P2RX3 (0.42) | DPP4ALDH1A1MAPTP2RX3TTR | |
| SCHEMBL27362167 | 0.86 | P2RX3 (0.42) | DPP4ALDH1A1MAPTP2RX3TTR | |
| SCHEMBL23446133 | 0.85 | MAPT (0.47) | DPP4ALDH1A1MAPTP2RX3TTR | |
| SCHEMBL29980453 | 0.85 | MAPT (0.47) | DPP4ALDH1A1MAPTP2RX3TTR | |
| SCHEMBL29838567 | 0.83 | DPP4 (0.45) | DPP4ALDH1A1MAPTP2RX3TTR | |
| SCHEMBL5363556 | 0.83 | DPP4 (0.45) | DPP4ALDH1A1MAPTP2RX3TTR | |
| SCHEMBL5363535 | 0.83 | DPP4 (0.45) | DPP4ALDH1A1MAPTP2RX3TTR | |
| SCHEMBL30883411 | 0.82 | MEN1 (0.42) | DPP4ALDH1A1MAPTP2RX3CCNC | |
| SCHEMBL14990673 | 0.80 | PLAU (0.43) | ALDH1A1MAPTCA1CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531498-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2012-12-12 | — | — | EP | disclosed |
| WO-2011097526-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2011-08-11 | — | — | WO | disclosed |