Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21125051 | 0.77 | GBA1 (0.52) | GBA1 | |
| SCHEMBL23308017 | 0.74 | GBA1 (0.34) | GBA1 | |
| SCHEMBL29472214 | 0.72 | ADORA3 (0.53) | GBA1 | |
| SCHEMBL18441261 | 0.70 | KMT2A (0.31) | — | |
| SCHEMBL17326936 | 0.70 | GBA1 (0.47) | GBA1 | |
| SCHEMBL29409194 | 0.69 | KMT2A (0.38) | — | |
| SCHEMBL29388972 | 0.69 | KMT2A (0.38) | — | |
| SCHEMBL21124664 | 0.69 | GBA1 (0.52) | GBA1 | |
| SCHEMBL22621294 | 0.69 | NAMPT (0.34) | — | |
| SCHEMBL23025256 | 0.69 | KDM4E (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210123922-A1 | APPLICATION OF CLICK CHEMISTRY FOR SIGNAL AMPLIFICATION IN IHC AND ISH ASSAYS | VENTANA MED SYST INC (US) | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210123922-A1 | APPLICATION OF CLICK CHEMISTRY FOR SIGNAL AMPLIFICATION IN IHC AND ISH ASSAYS | MKI67, TIE1, ALK | HSPA5 4577/4885HSPA9 4341/4885GBA1 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.