Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.59 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.59 |
| ▸ | PAK4 | O96013 | 1/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | RET | P07949 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
| ▸ | PRKACA | P17612 | 1/20 | 0.59 |
| ▸ | FLT1 | P17948 | 1/20 | 0.59 |
| ▸ | LTK | P29376 | 1/20 | 0.59 |
| ▸ | GRK5 | P34947 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23426075 | 0.83 | PIM1 (0.58) | MAP4K4CLK4AURKADAPK3JAK2 | |
| SCHEMBL30719601 | 0.81 | ADORA2A (0.57) | MAP4K4CLK4AURKADAPK3JAK2 | |
| SCHEMBL23496977 | 0.81 | ADORA2A (0.57) | MAP4K4CLK4AURKADAPK3JAK2 | |
| SCHEMBL29986591 | 0.78 | ADORA2A (0.72) | MAP4K4ADORA2AGRM4KITPIK3CD | |
| SCHEMBL29986490 | 0.78 | ADORA2A (0.72) | METKDRADORA2ACAMKK1CAMKK2 | |
| SCHEMBL17666810 | 0.78 | ADORA2A (0.72) | MAP4K4ADORA2AGRM4KITPIK3CD | |
| SCHEMBL23259465 | 0.78 | ADORA2A (0.67) | MAP4K4CLK4DAPK3PIM1PRKACA | |
| SCHEMBL12357140 | 0.78 | ADORA2A (0.72) | METKDRADORA2ACAMKK1CAMKK2 | |
| SCHEMBL29987357 | 0.78 | ADORA2A (0.66) | MAP4K4CLK4METKDRADORA2A | |
| SCHEMBL28872931 | 0.78 | ADORA2A (0.66) | MAP4K4METKDRADORA2ACAMKK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122774-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122774-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND | L1CAM, NOM1, MSL1 | MAP4K4 3786/4885CLK4 1813/4885AURKA 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.