Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 15/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 14/20 | 0.39 |
| ▸ | TSHR | P16473 | 12/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.39 |
| ▸ | USP2 | O75604 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30106843 | 0.81 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL29610876 | 0.79 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL24314268 | 0.79 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL29611607 | 0.78 | ADORA1 (0.54) | ADORA3 | |
| SCHEMBL27090409 | 0.78 | ADORA1 (0.54) | ADORA3 | |
| SCHEMBL29611653 | 0.77 | ADORA3 (0.43) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL24313565 | 0.77 | ADORA3 (0.43) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL24313850 | 0.77 | PRMT5 (0.47) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL29610954 | 0.77 | PRMT5 (0.47) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL29611468 | 0.77 | PRMT5 (0.47) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021079196-A2 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2021-04-29 | — | — | WO | disclosed |