Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.62 |
| ▸ | METTL3 | Q86U44 | 16/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23313248 | 0.84 | PRMT5 (0.57) | PRMT5METTL3 | |
| SCHEMBL23313257 | 0.76 | METTL3 (1.00) | PRMT5METTL3 | |
| SCHEMBL23313083 | 0.74 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL25015696 | 0.74 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL25015669 | 0.73 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL24628054 | 0.73 | METTL3 (1.00) | PRMT5METTL3 | |
| SCHEMBL23273846 | 0.72 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL29772278 | 0.72 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL23313253 | 0.72 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL25015676 | 0.71 | METTL3 (1.00) | PRMT5METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021079196-A2 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2021-04-29 | — | — | WO | disclosed |