Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 17/20 | 0.87 |
| ▸ | PRMT5 | O14744 | 12/20 | 0.87 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25015688 | 0.93 | METTL3 (1.00) | METTL3PRMT5WDR77 | |
| SCHEMBL23313892 | 0.81 | METTL3 (1.00) | METTL3PRMT5WDR77 | |
| SCHEMBL23313123 | 0.81 | METTL3 (1.00) | METTL3PRMT5WDR77 | |
| SCHEMBL23313071 | 0.79 | METTL3 (0.84) | METTL3PRMT5WDR77 | |
| SCHEMBL25015495 | 0.79 | METTL3 (0.84) | METTL3PRMT5WDR77 | |
| SCHEMBL25017589 | 0.78 | PRMT5 (1.00) | METTL3PRMT5WDR77 | |
| SCHEMBL18571839 | 0.78 | PRMT5 (1.00) | METTL3PRMT5WDR77 | |
| SCHEMBL23313262 | 0.78 | METTL3 (1.00) | METTL3PRMT5WDR77 | |
| SCHEMBL18571790 | 0.77 | PRMT5 (0.81) | METTL3PRMT5WDR77 | |
| SCHEMBL18571673 | 0.77 | PRMT5 (1.00) | METTL3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021079196-A2 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2021-04-29 | — | — | WO | disclosed |