Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 11/20 | 0.79 |
| ▸ | METTL3 | Q86U44 | 11/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23313273 | 0.90 | METTL3 (0.87) | PRMT5METTL3 | |
| SCHEMBL23313145 | 0.90 | METTL3 (0.78) | PRMT5METTL3 | |
| SCHEMBL23313037 | 0.89 | METTL3 (0.88) | PRMT5METTL3 | |
| SCHEMBL23313081 | 0.88 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL23313051 | 0.87 | METTL3 (1.00) | PRMT5METTL3 | |
| SCHEMBL25015997 | 0.87 | PRMT5 (0.60) | PRMT5METTL3 | |
| SCHEMBL23313271 | 0.87 | METTL3 (0.91) | PRMT5METTL3 | |
| SCHEMBL23313941 | 0.86 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL23313267 | 0.86 | PRMT5 (0.74) | PRMT5METTL3 | |
| SCHEMBL23313286 | 0.86 | METTL3 (0.80) | PRMT5METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021079196-A2 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2021-04-29 | — | — | WO | disclosed |