SCHEMBL23314748

SCHEMBL23314748

C#C[C@H](N)C(O)CNC=O

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5650449 0.74
SCHEMBL28150968 0.72
SCHEMBL17275391 0.72
SCHEMBL16384297 0.71
SCHEMBL11343452 0.67 ADH1B (0.44) ADH1BADH1CADH1A
SCHEMBL11477895 0.66 ADH1B (0.48) ADH1BADH1CADH1A
SCHEMBL14280503 0.65 ADH1B (0.38) ADH1BADH1CADH1A
SCHEMBL3670984 0.65
SCHEMBL23766640 0.65 ADH1B (0.52) ADH1BADH1CADH1A
SCHEMBL7045031 0.64 KDM4E (0.46) ADH1BADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3145944-B1 MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS RQX PHARMACEUTICALS INC (US) 2021-05-05 EP disclosed