Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23314541 | 1.00 | TDP1 (0.30) | TDP1 | |
| SCHEMBL23736267 | 0.91 | SIGMAR1 (0.33) | TDP1 | |
| SCHEMBL23314776 | 0.82 | RET (0.34) | — | |
| SCHEMBL24490416 | 0.81 | — | — | |
| SCHEMBL23864847 | 0.80 | — | — | |
| SCHEMBL24490422 | 0.78 | OPRL1 (0.37) | TDP1 | |
| SCHEMBL19688919 | 0.76 | — | — | |
| SCHEMBL24518320 | 0.75 | — | — | |
| SCHEMBL23864904 | 0.70 | — | — | |
| SCHEMBL15203160 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922829-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-08-11 | — | — | EP | disclosed |
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |