Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 7/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315327 | 1.00 | AGTR2 (0.42) | AGTR2AGTR1HCRTR2TMEM97SIGMAR1 | |
| SCHEMBL23315251 | 0.89 | AGTR2 (0.51) | AGTR2AGTR1HCRTR2TMEM97SIGMAR1 | |
| SCHEMBL23315257 | 0.88 | AGTR2 (0.43) | AGTR2AGTR1HCRTR2TMEM97SIGMAR1 | |
| SCHEMBL23315229 | 0.88 | AGTR2 (0.43) | AGTR2AGTR1HCRTR2TMEM97SIGMAR1 | |
| SCHEMBL23315455 | 0.88 | AGTR2 (0.43) | AGTR2AGTR1HCRTR2TMEM97SIGMAR1 | |
| SCHEMBL23315338 | 0.86 | AGTR2 (0.57) | AGTR2AGTR1HCRTR2ACACBALDH1A1 | |
| SCHEMBL23315290 | 0.86 | AGTR2 (0.57) | AGTR2AGTR1HCRTR2ACACBALDH1A1 | |
| SCHEMBL23315558 | 0.83 | AGTR2 (0.59) | AGTR2AGTR1 | |
| SCHEMBL21881426 | 0.83 | AGTR2 (0.59) | AGTR2AGTR1 | |
| SCHEMBL21881321 | 0.83 | AGTR2 (0.59) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3620454-B1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |