SCHEMBL23315293

SCHEMBL23315293

CCCCOC(C(=O)N1Cc2ccc(OC)c(OCc3ccccc3)c2CC1C(=O)OCC)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 19/20 0.77
AGTR1 P30556 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21881546 1.00 AGTR2 (0.77) AGTR2AGTR1
SCHEMBL23315175 0.93 AGTR2 (0.78) AGTR2AGTR1
SCHEMBL21881621 0.93 AGTR2 (0.78) AGTR2AGTR1
SCHEMBL21881483 0.92 AGTR2 (0.74) AGTR2AGTR1
SCHEMBL21881127 0.92 AGTR2 (0.74) AGTR2AGTR1
SCHEMBL21881632 0.92 AGTR2 (0.74) AGTR2AGTR1
SCHEMBL21881126 0.92 AGTR2 (0.74) AGTR2AGTR1
SCHEMBL21881131 0.92 AGTR2 (0.74) AGTR2AGTR1
SCHEMBL21881125 0.92 AGTR2 (0.74) AGTR2AGTR1
SCHEMBL23315283 0.89 AGTR2 (0.76) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3620454-B1 CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2021-05-05 EP disclosed