Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 16/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23315639 | 0.97 | AGTR2 (0.52) | AGTR2AGTR1ACACBHCRTR2 | |
| SCHEMBL23315338 | 0.94 | AGTR2 (0.57) | AGTR2AGTR1ACACBHCRTR2CPT2 | |
| SCHEMBL23315290 | 0.94 | AGTR2 (0.57) | AGTR2AGTR1ACACBHCRTR2CPT2 | |
| SCHEMBL23315354 | 0.88 | AGTR2 (0.55) | AGTR2AGTR1HCRTR2CPT2CPT1A | |
| SCHEMBL23315229 | 0.86 | AGTR2 (0.43) | AGTR2AGTR1ACACBHCRTR2 | |
| SCHEMBL23315554 | 0.85 | AGTR2 (0.53) | AGTR2AGTR1ACACBHCRTR2 | |
| SCHEMBL21881439 | 0.85 | AGTR2 (0.69) | AGTR2AGTR1 | |
| SCHEMBL21881438 | 0.85 | AGTR2 (0.69) | AGTR2AGTR1 | |
| SCHEMBL23315301 | 0.85 | AGTR2 (0.69) | AGTR2AGTR1 | |
| SCHEMBL21881314 | 0.85 | AGTR2 (0.69) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3620454-B1 | CARBOXYLIC ACID DERIVATIVE AS AT2R RECEPTOR ANTAGONIST | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-05 | — | — | EP | disclosed |